Molecular Weight. Chemical Formula. The increase in cAMP causes relaxation of bronchial smooth muscle. Indications This job aid also provides an overview of the approved security classification documents that assist in analyzing and evaluating … Xanthine Derivatives. Theophylline relaxes bronchial smooth muscle by inhibition of the enzyme phosphodiesterase and suppresses airway responsiveness to stimuli that cause bronchoconstriction. Classifications of bronchodilators include beta 2-agonists, anticholinergics, and xanthine derivatives. 152. Xanthine DerivativesXanthine derivatives such as theophylline inhibit phosphodiesterase, resulting in an increase in cAMP. C5-H4-N4-O2. Inhalation and Intranasal spray. Anti-inflammatory. Derivatives of xanthine (known collectively as xanthines) are a group of alkaloids commonly used for their effects as mild stimulants and as bronchodilators, notably in the treatment of asthma or influenza symptoms. These medications open the airways, but they work on different receptors in the body. resulting from hydroxylation of Xanthine derivatives (uric acid derivatives) or demethylation products showed to be able to repair radicals resulting from adenine oxidation [12]. 5.14 Xanthine Derivatives Open Resources for Nursing (Open RN) Theophylline is a xanthine derivative. Two xanthine derivatives with high affinity and high selectivity for adenosine A 1 receptor, 8-cyclopentyl-1,3-dipropylxanthine (DPCPX) (Lohse et al., 1987) and its analog 8-dicyclopropylmethyl-1,3-dipropylxanthine (KF15372) (Shimada et al., 1991), were selected as lead compounds for in vivo imaging. In contrast to other, more potent stimulants like sympathomimetic amines, xanthines … Xanthine derivative Mast Cell Stabilizers. Therapeutic Categories. Derivative Classification Training The purpose of this job aid is to provide quick reference information for the responsibilities and procedures associated with derivative classification. Xanthine derivatives Accession Number DBCAT001034 (DBCAT000503, DBCAT001028, DBCAT001220, DBCAT002203, DBCAT002692, DBCAT003295) Description. Clinical significance. 48:12.12 Xanthine Derivatives* 48:16 Expectorants 48:24 Mucolytic Agents* 48:36 Pulmonary Surfactants 48:48 Vasodilating Agents* 48:92 Respiratory Agents, Miscellaneous 52:00 Eye, Ear, Nose, and Throat (EENT) Preparations 52:02 Antiallergic Agents 52:04 Anti-infectives 52:04.04 Antibacterials 52:04.16 … The xanthine derivatives are agents that resemble natural occurring xanthines such as caffeine, theobromine and methylxanthines. Ipratropium Bromide administration. ... Ipratropium Bromide classification. Decrease inflammation. Theophylline competitively blocks phosphodiesterase which increases cAMP tissue concentrations causing bronchodilatation, diuresis, CNS and cardiac stimulation, and gastric acid secretion. Anticholingeric Agent. As a member of the xanthine family, it bears structural and pharmacological similarity to theobromine … In the case of antipyrine derivatives demethylation reactions from the amino group induced by the hydroxyl radical were also … Classification: Bronchodilator, Xanthine. Bronchial dilation and increase focus of contraction of diaphragmatic muscle. The major pharmacologic actions of the xanthines are inhibition of tissue phosphodiesterases which i … These are plant alkaloids and components of coffee, tea and chocolate. Pregnancy Category C Therapeutic actions. A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanism of Action. 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